CEBPE Antibody
Product Sizes
20 ug
£364.00
1053-MSM2-P0-20UG
About this Product
- SKU:
- 1053-MSM2-P0
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-CEBPE-1G12
- Clonality:
- Monoclonal
- Extra Details:
- The transcription factor C/EBP α (CCAAT-enhancer binding protein) is a heatstable; sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP α regulates gene expression in a variety of tissues including liver; adipose; lung and intestine. C/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP α appears to function exclusively in terminally differentiated; growth-arrested cells. Additional family members include C/EBP β; C/EBP γ; C/EBP δ and C/EBP ε; all of which exhibit similar DNA-binding specificities and affinities to C/EBP α. Furthermore; C/EBP β and C/EBP δ readily form heterodimers both with each other as well as with C/EBP α.
- Host:
- Mouse
- Immunogen:
- Recombinant human CEBPE protein
- Isotype:
- IgG2a
- Molecular Weight:
- 32/30/27/14kDa
- Research Area:
- Developmental Biology; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132657
