CARM1 Antibody
Product Sizes
100 ug
£671.00
10498-MSM3-P1ABX-100UG
About this Product
- SKU:
- 10498-MSM3-P1ABX
- Additional Names:
- Coactivator-associated arginine methyltransferase 1 | Protein arginine N-methyltransferase 4
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CARM1/7426
- Clonality:
- Monoclonal
- Extra Details:
- CARM1 (coactivator-associated arginine methyltransferase 1); also known as protein arginine N-methyltransferase 4 (PRMT4); is a 585 amino acid nuclear and cytoplasmic protein belonging to the protein arginine N-methyltransferase family. As a protein arginine N-methyltransferase; CARM1 is capable of catalyzing the transfer of methyl groups from S-adenosylmethionine to the guanidino group nitrogen atoms of arginine residues in certain proteins involved in mRNA stability; DNA packaging and transcriptional regulation. The methyltransferase activity of CARM1 has been found to be negatively regulated through phosphorylation at a conserved serine residue. CARM1 acts as a positive regulator for multiple transcription factors and functions as a secondary coactivator through its association with p160 coactivators. CARM1 exists as two alternatively spliced isoforms; and is encoded by a gene that maps to human chromosome 19p13.2.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa200-400) of human CARM1 protein (exact sequence is proprietary)
- Isotype:
- IgG2
- Molecular Weight:
- 64/45 kDa (isoform 1 / isoform 2)
- Research Area:
- Developmental Biology; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=129037
