Interferon regulatory factor 9 / IRF-9 Antibody
Product Sizes
100 ug
£671.00
10379-MSM2-P1ABX-100UG
About this Product
- SKU:
- 10379-MSM2-P1ABX
- Additional Names:
- IFN-alpha-responsive transcription factor subunit | ISGF3 p48 subunit | Interferon-stimulated gene factor 3 gamma | Transcriptional regulator ISGF3 subunit gamma
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-IRF9-2F8
- Clonality:
- Monoclonal
- Extra Details:
- Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors; Jak kinases (TYK2 and JAK1) are activated; leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize; associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor; that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes; which drive the cell in an antiviral state.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human IRF9 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 43.34kDa
- Research Area:
- Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=111665
