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Antibodies

p27Kip1 (Mitotic Inhibitor/Suppressor Protein) Antibody

Product Sizes
100 ug
£671.00
1027-MSM3-P1-100UG
About this Product
SKU:
1027-MSM3-P1
Additional Names:
Cyclin-dependent kinase inhibitor p27 | p27Kip1
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
DCS-72.F6
Clonality:
Monoclonal
Extra Details:
Recognizes a 27kDa protein; identified as the p27Kip1; a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Host:
Mouse
Immunogen:
Recombinant full-length Mouse p27 protein
Isotype:
IgG1
Molecular Weight:
25-26kDa
Research Area:
AKT Signaling; Cancer; Cardiovascular; Cytokine Signaling; Hypoxia; Immunology; Infectious Disease; Lung Cancer; Nuclear Marker; Ovarian Cancer; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody