Recombinant p21WAF1 (Tumor Suppressor Protein) Antibody
Product Sizes
100 ug
£671.00
1026-MSM11-P1ABX-100UG
About this Product
- SKU:
- 1026-MSM11-P1ABX
- Additional Names:
- CDK-interacting protein 1 | Melanoma differentiation-associated protein 6 | p21
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rCIP1/6907
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a 21kDa protein; identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type; but not mutant; p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma; non-small cell lung carcinoma; thyroid carcinoma).
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-100) of human p21 (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 21kDa
- Research Area:
- AKT Signaling; Bladder Cancer; Breast Cancer; Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Lung Cancer; Nuclear Marker; Ovarian Cancer; Sign
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=111544
