Recombinant CDK4 Antibody
Product Sizes
100 ug
£671.00
1019-RBM1-P1ABX-100UG
About this Product
- SKU:
- 1019-RBM1-P1ABX
- Additional Names:
- Cell division protein kinase 4 | PSK-J3
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CDK4/7987R
- Clonality:
- Monoclonal
- Extra Details:
- Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level (PMID:17253961). CCND1- CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth (PMID:21844184). CDK4 is highly expressed in highly differentiated and dedifferentiated liposarcomas; but rarely expressed in other benign liposarcomas and other sarcomas. CDK4 and MDM2 combined to differentiate between highly differentiated liposarcoma (+); dedifferentiated liposarcoma (+) and myxoid liposarcoma; pleomorphic liposarcoma; spindle lipoma; pleomorphic lipoma and other high-grade sarcomas.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment corresponding to N-terminal of human CDK4 protein
- Isotype:
- IgG
- Molecular Weight:
- 34kDa
- Research Area:
- Bladder Cancer; Breast Cancer; Cardiovascular; Developmental Biology; Infectious Disease; Lung Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132626
