Recombinant Cadherin 17 / LI Cadherin (Gastric Adenocarcinoma Marker) Antibody
Product Sizes
100 ug
£671.00
1015-RBM15-P1-100UG
About this Product
- SKU:
- 1015-RBM15-P1
- Additional Names:
- Intestinal peptide-associated transporter HPT-1 | Liver-intestine cadherin
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CDH17/8515R
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of 120kDa; which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus; which is characterized by a series of five homologous repeats; the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal; intracellular domain interacts with a variety of cytoplasmic proteins; including beta-catenin; to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 120kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128281
