Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody
Product Sizes
100 ug
£671.00
1014-MSM1X-P1-100UG
About this Product
- SKU:
- 1014-MSM1X-P1
- Additional Names:
- Kidney-specific cadherin
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- SPM594
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 130kDa; identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis; tissue morphogenesis; tissue structure maintenance; cell polarization; neoplastic invasiveness and metastasis; and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney; Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells; and not in glomeruli; renal interstitial cells; or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CDH16 protein
- Isotype:
- IgG1
- Molecular Weight:
- 130kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=111454
