MICA Antibody
Product Sizes
100 ug
£671.00
100507436-MSM2-P1-100UG
About this Product
- SKU:
- 100507436-MSM2-P1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MICA/4442
- Clonality:
- Monoclonal
- Extra Details:
- MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with β-2-microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial Vδ1 γδ T cells expressing variable TCRs; suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human MICA (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 92kDa
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=111451
