Recombinant Cadherin-6 (CDH6) / K-Cadherin Antibody
Product Sizes
100 ug
£671.00
1004-RBM4-P1-100UG
About this Product
- SKU:
- 1004-RBM4-P1
- Additional Names:
- Kidney cadherin
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CDH6/9300R
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner; contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines; suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Cadherin 6 protein (CDH6) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 130kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127149
