N-Cadherin / Cadherin-2 / CD325 (NCAD) Antibody
Product Sizes
20 ug
£364.00
1000-MSM3-P0-20UG
About this Product
- SKU:
- 1000-MSM3-P0
- Additional Names:
- CDw325 | Neural cadherin
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CDH2/1573
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of ~140kDa; identified as N-Cadherin (NCAD); also known as CD325. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. Expression of N-cadherin has been reported on a variety of normal tissues including neuronal; endothelial and muscle cells; and a subpopulation of early hematopoietic progenitor cells. Results aid in the classification of malignant non-carcinomatous neoplasms including mesotheliomas; chordomas; synovial sarcomas; malignant melanomas; epithelioid sarcomas; epithelioid angiosarcomas; clear cell sarcomas as well as serous and endometrioid tumors of the ovary have been demonstrated to be N-cadherin positive; whereas mucinous tumors are negative. Other N-cadherin-positive neoplasms include renal cell carcinomas and some variant breast tumors; including medullary breast carcinomas and sarcomatoid metaplastic breast carcinomas.
- Host:
- Mouse
- Immunogen:
- Recombinant human CDH2 intracellular domain
- Isotype:
- IgG1
- Molecular Weight:
- 130-140kDa
- Research Area:
- Autophagy; Cardiovascular; Developmental Biology; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=111393
