Rabbit anti-MGMT antibody, clone SQab1861 (monoclonal)
Product Sizes
100 ul
£671.00
MON240132-100UL
About this Product
- SKU:
- MON240132
- Application:
- Flow Cytometry, IHC-Paraffin, Immunoprecipitation, Western Blot
- translate.label.attr.clone:
- SQab1861
- Clonality:
- Monoclonal
- Extra Details:
- Application note: IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. MGMT is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide around the N-terminus of Human MGMT.
- Purification:
- Protein A Purified; Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Monosan
- Type:
- Antibody: Monoclonal Antibody
