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Antibodies

Rabbit anti-CD279 / PD-1 antibody, clone SQab1732 (monoclonal)

Product Sizes
100 ul
£671.00
MON240119-100UL
About this Product
SKU:
MON240119
Application:
Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
translate.label.attr.clone:
SQab1732
Clonality:
Monoclonal
Extra Details:
Application note: IHC-P: Antigen Retrieval: Boil tissue section in Tris/EDTA buffer (pH 9.0).* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: CD279 / PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
Recombinant full length protein of Human PD-1. The immunogen contains the specific extracellular domain of Human PD-1 (Leu25 - Gln167).
Purification:
Protein A Purified; Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Monosan
Type:
Antibody: Monoclonal Antibody