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Antibodies

TFPI antibody, C-term

Product Sizes
100 ug
£ POA
GTX89985-100UG
About this Product
SKU:
GTX89985
Additional Names:
tissue factor pathway inhibitor , EPI , LACI , TFI , TFPI1
Application:
Western Blot
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Clonality:
Polyclonal
Concentration:
0.50 mg/ml
Extra Details:
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Host:
Goat
Immunogen:
Peptide with sequence C-VKIAYEEIFVKNM, from the C Terminus of the protein sequence according to NP_006278.1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is expected to recognize isoform a (NP_006278.1) only.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody
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