APE1 blocking peptide
Product Sizes
100 ug
£ POA
GTX89912-PEP-100UG
About this Product
- SKU:
- GTX89912-PEP
- Additional Names:
- Apurinic/Apyrimidinic Endodeoxyribonuclease 1 , Ape , Ape1 , Apen , Apex , Apx , Hap1 , Ref1 , Apex1
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Extra Details:
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
- Immunogen:
- APEX nuclease (multifunctional DNA repair enzyme) 1
- Physical State:
- Lyophilized
- Shipping Conditions:
- Blue Ice
- Specificity:
- The peptide was used in the production of GTX89912.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:Download
