FE65 antibody, C-term
Product Sizes
100 ug
£ POA
GTX89278-100UG
About this Product
- SKU:
- GTX89278
- Additional Names:
- amyloid beta precursor protein binding family B member 1 , FE65 , MGC:9072 , RIR
- Application:
- Western Blot
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 0.50 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
- Host:
- Goat
- Immunogen:
- Peptide with sequence C-GSLKPKRLGAHTP, from the C Terminus of the protein sequence according to NP_001155.1; NP_663722.1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is expected to recognise both reported isoforms (NP_001155.1 and NP_663722.1).
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
