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Antibodies

IL1 Receptor 2 antibody, Internal

Product Sizes
100 ug
£486.00
GTX88100-100UG
About this Product
SKU:
GTX88100
Additional Names:
interleukin 1 receptor type 2 , CD121b , CDw121b , IL-1R-2 , IL-1RT-2 , IL-1RT2 , IL1R2c , IL1RB
Application:
Western Blot
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Clonality:
Polyclonal
Concentration:
0.50 mg/ml
Extra Details:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
Host:
Goat
Immunogen:
Peptide with sequence C-QYNITRSIELRIKK, from the internal region of the protein sequence according to NP_004624.1; NP_001248348.1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is expected to cross-react with both reported isoforms (NP_004624.1; NP_001248348.1).
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody