APC13 antibody
Product Sizes
100 ug
£509.00
GTX85186-100UG
About this Product
- SKU:
- GTX85186
- Additional Names:
- anaphase promoting complex subunit 13 , APC13 , SWM1
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS, 0.02% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
- Host:
- Rabbit
- Immunogen:
- APC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13.The immunogen is located within the last 50 amino acids of APC13.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
