RUNX2 antibody
Product Sizes
400 ul
£486.00
GTX81326-400UL
About this Product
- SKU:
- GTX81326
- Additional Names:
- runt related transcription factor 2 , AML3 , CBF-alpha-1 , CBFA1 , CCD , CCD1 , CLCD , OSF-2 , OSF2 , PEA2aA , PEBP2aA
- Application:
- Flow Cytometry, IHC-Paraffin, Western Blot
- Buffer:
- PBS, 0.09% Sodium azide.
- Clonality:
- Polyclonal
- Extra Details:
- This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide between 445-474 amino acids of human RUNX2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified; Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
