CD16 antibody [MEM-154] (FITC)
Product Sizes
100 tests
£337.00
GTX79997-100TESTS
About this Product
- SKU:
- GTX79997
- Additional Names:
- CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a
- Application:
- Flow Cytometry
- Buffer:
- PBS, 15mM Sodium azide.
- translate.label.attr.clone:
- MEM-154
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Human granulocytes
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Size-exclusion Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody reacts with an epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop).
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
