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Antibodies

CD68 antibody [514H12]

Product Sizes
50 ul
£185.00
GTX75390-50UL
About this Product
SKU:
GTX75390
Additional Names:
CD68 molecule , GP110 , LAMP4 , SCARD1
Application:
IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
Tissue culture supernatant, 0.09% Sodium azide.
translate.label.attr.clone:
514H12
Clonality:
Monoclonal
Extra Details:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Fusion protein corresponding to external domain of human CD68.
Isotype:
IgG2a
Physical State:
Liquid
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody