CD8 antibody [2ST8.5H7]
Product Sizes
200 ug
£760.00
GTX75282-200UG
About this Product
- SKU:
- GTX75282
- Additional Names:
- P37 Antibody , LYT3 Antibody , CD8B Antibody , LY3 Antibody , LEU2 Antibody , CD8b molecule Antibody , CD8B1 Antibody
- Application:
- Flow Cytometry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 1% BSA, no preservatives.
- translate.label.attr.clone:
- 2ST8.5H7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
- Host:
- Mouse
- Immunogen:
- Normal human T lymphocytes
- Isotype:
- IgG2a
- Physical State:
- Liquid
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody binds to the beta chain, recognising an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
