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Antibodies

CD16 antibody [LNK16]

Product Sizes
100 ug
£ POA
GTX74720-100UG
About this Product
SKU:
GTX74720
Additional Names:
CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a
Application:
Flow Cytometry, Immunoprecipitation
Buffer:
TBS, 15mM Sodium azide.
translate.label.attr.clone:
LNK16
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Normal human peripheral blood granulocytes
Isotype:
IgG1
Physical State:
Liquid
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody
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