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Antibodies

CD86 antibody [BU63] (PE)

Product Sizes
100 tests
GTX74652-100TESTS
About this Product
SKU:
GTX74652
Additional Names:
CD86 molecule , B7-2 , B7.2 , B70 , CD28LG2 , LAB72
Application:
Flow Cytometry
Buffer:
PBS, 1% BSA, 5% Sucrose, 0.09% Sodium azide.
translate.label.attr.clone:
BU63
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Host:
Mouse
Immunogen:
Human peripheral blood lymphocytes.
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, clone Bu63 is located within the Ig-v-like domain of human CD86 (Jeanin et al. 1997).
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody