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Antibodies

CD68 antibody [PG-M1]

Product Sizes
500 ul
£650.00
GTX73723-500UL
About this Product
SKU:
GTX73723
Additional Names:
CD68 molecule , GP110 , LAMP4 , SCARD1
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Buffer:
Tissue culture supernatant, 0.09% Sodium azide.
translate.label.attr.clone:
PG-M1
Clonality:
Monoclonal
Extra Details:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
BALB/C mice were immunized with Gaucher's cells.
Isotype:
IgG3
Physical State:
Liquid
Purification:
Unpurified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody