Human PPM1F protein, His tag
Product Sizes
100 ug
£ POA
GTX68086-PRO-100UG
About this Product
- SKU:
- GTX68086-PRO
- Additional Names:
- protein phosphatase, Mg2+/Mn2+ dependent 1F , CAMKP , CaMKPase , FEM-2 , POPX2 , hFEM-2
- Buffer:
- 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, no preservatives.
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- Immunogen:
- protein phosphatase, Mg2+/Mn2+ dependent 1F
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
