Human AMPK beta 1 protein, His tag
Product Sizes
10 ug
£317.00
GTX67668-PRO-10UG
About this Product
- SKU:
- GTX67668-PRO
- Additional Names:
- protein kinase AMP-activated non-catalytic subunit beta 1 , AMPK , HAMPKb
- Buffer:
- 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
- Immunogen:
- protein kinase AMP-activated non-catalytic subunit beta 1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
