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Proteins and Peptides

Human SEPT5 protein, His tag

Product Sizes
100 ug
£335.00
GTX67645-PRO-100UG
About this Product
SKU:
GTX67645-PRO
Additional Names:
septin 5 , CDCREL , CDCREL-1 , CDCREL1 , H5 , HCDCREL-1 , PNUTL1
Buffer:
20mM Tris-HCl, 300mM NaCl, 40% Glycerol, 1mM DTT, no preservatives.
Concentration:
0.25 mg/ml
Extra Details:
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
Immunogen:
septin 5
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes