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Proteins and Peptides

Human Ogg1 protein, His tag

Product Sizes
100 ug
£335.00
GTX67604-PRO-100UG
About this Product
SKU:
GTX67604-PRO
Additional Names:
8-oxoguanine DNA glycosylase , HMMH , HOGG1 , MUTM , OGH1
Buffer:
20mM Tris-HCl, 100mM NaCl, 40% Glycerol, no preservatives.
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
Immunogen:
8-oxoguanine DNA glycosylase
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes