Human Sorbitol Dehydrogenase protein (active)
Product Sizes
10 ug
£204.00
GTX67160-PRO-10UG
About this Product
- SKU:
- GTX67160-PRO
- Additional Names:
- sorbitol dehydrogenase , HEL-S-95n , SORD1
- Application:
- Cell-based/Functional Assay
- Buffer:
- 20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservatives.
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
- Immunogen:
- sorbitol dehydrogenase
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
