Human PIN1 protein (active)
Product Sizes
100 ug
£335.00
GTX67121-PRO-100UG
About this Product
- SKU:
- GTX67121-PRO
- Additional Names:
- peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , DOD , UBL5
- Application:
- Cell-based/Functional Assay
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, 5mM DTT, no preservatives.
- Concentration:
- 1 mg/ml
- Extra Details:
- Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- Immunogen:
- peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
