Human IDO1 protein, His tag (active)
Product Sizes
20 ug
£224.00
GTX67055-PRO-20UG
About this Product
- SKU:
- GTX67055-PRO
- Additional Names:
- indoleamine 2,3-dioxygenase 1 , IDO , IDO-1 , INDO
- Application:
- Cell-based/Functional Assay
- Buffer:
- 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, no preservatives.
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Immunogen:
- indoleamine 2,3-dioxygenase 1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:Download
