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Proteins and Peptides

Human Glutamine synthetase protein (active)

Product Sizes
20 ug
GTX67011-PRO-20UG
About this Product
SKU:
GTX67011-PRO
Additional Names:
glutamate-ammonia ligase , GLNS , GS , PIG43 , PIG59
Application:
Cell-based/Functional Assay
Buffer:
20mM Tris-HCl, 10% Glycerol, 1mM DTT, 0.1mM PMSF, no preservatives.
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Immunogen:
glutamate-ammonia ligase
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes