CCR1 antibody [HL3023]
Product Sizes
25 ul
£139.00
GTX640436-25UL
100 ul
£354.00
GTX640436-100UL
About this Product
- SKU:
- GTX640436
- Additional Names:
- C-C motif chemokine receptor 1 , CD191 , CKR-1 , CKR1 , CMKBR1 , HM145 , MIP1aR , SCYAR1
- Application:
- IHC-Paraffin, Immunocytochemistry, Immunofluorescence
- Buffer:
- PBS, no preservatives.
- translate.label.attr.clone:
- HL3023
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide encompassing a sequence within the Extracellular domain of human CCR1. The exact sequence is proprietary.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for human CCR1 protein and does not cross react with human CCR2, CCR4, CCR5, CCR7, CCR9, and CCR10 protein.<br>This antibody was raised against human CCR1 Extracellular domain.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Download
