CCR10 antibody [HL2852]
Product Sizes
25 ul
£139.00
GTX640123-25UL
100 ul
£354.00
GTX640123-100UL
About this Product
- SKU:
- GTX640123
- Additional Names:
- C-C motif chemokine receptor 10 , GPR2
- Application:
- Cell-based/Functional Assay, Immunocytochemistry, Immunofluorescence
- Buffer:
- PBS, no preservatives.
- translate.label.attr.clone:
- HL2852
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide encompassing a sequence within the Extracellular domain human of CCR10. The exact sequence is proprietary.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for human CCR10 protein and does not cross react with human CCR1, CCR2, CCR4, CCR5, CCR7, and CCR9 protein.<br>This antibody was raised against human CCR10 Extracellular domain.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Download
