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Antibodies

CCR1 antibody [HL2840]

Product Sizes
25 ul
£139.00
GTX640111-25UL
100 ul
£354.00
GTX640111-100UL
About this Product
SKU:
GTX640111
Additional Names:
C-C motif chemokine receptor 1 , CD191 , CKR-1 , CKR1 , CMKBR1 , HM145 , MIP1aR , SCYAR1
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS, no preservatives.
translate.label.attr.clone:
HL2840
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the Intracellular domain of human CCR1. The exact sequence is proprietary.
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Feline, Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody was raised against human CCR1 Intracellular domain.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Recombinant Antibodies