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Antibodies

IL1 beta antibody [GT289]

Product Sizes
25 ul
£139.00
GTX634188-25UL
100 ul
£354.00
GTX634188-100UL
About this Product
SKU:
GTX634188
Additional Names:
interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS, no preservatives.
translate.label.attr.clone:
GT289
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]
Host:
Mouse
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL1 beta. The exact sequence is proprietary.
Isotype:
IgG2a
Physical State:
Liquid
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody