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Antibodies

RUNX3 antibody [2B3]

Product Sizes
100 ug
£486.00
GTX60639-100UG
About this Product
SKU:
GTX60639
Additional Names:
runt related transcription factor 3 , AML2 , CBFA3 , PEBP2aC
Application:
ELISA, Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS, 0.05% Sodium azide.
translate.label.attr.clone:
2B3
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.
Isotype:
IgG2b
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody