Nectin 1 antibody
Product Sizes
50 ul
£858.00
GTX54843-50UL
About this Product
- SKU:
- GTX54843
- Additional Names:
- nectin cell adhesion molecule 1 , CD111 , CLPED1 , ED4 , HIgR , HV1S , HVEC , OFC7 , PRR , PRR1 , PVRL1 , PVRR , PVRR1 , SK-12 , nectin-1
- Application:
- Flow Cytometry, IHC-Frozen, Imaging, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 1% BSA, 0.05% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
- Host:
- Rabbit
- Immunogen:
- Peptide (C)GKPPSVVSWETRLK, corresponding to amino acid residues 177-190 (Extracellular, N-terminus) of human Nectin-1 (Accession : Q15223).
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody will recognize all known isoforms of Nectin-1, including the secreted form (also known as isoform gamma).
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
