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Antibodies

Integrin beta 1 / CD29 antibody [BV7]

Product Sizes
50 ug
£458.00
GTX54427-50UG
About this Product
SKU:
GTX54427
Additional Names:
CD29,FNRB,GPIIA,ITGB1,MDF2,MSK12,VLAB,VLABETA,integrin subunit beta 1,Integrin beta 1,B1 Integrin,B Beta1 integrin
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Immunoprecipitation, Western Blot
Buffer:
Filter-sterilized PBS, 0.1% BSA, no preservatives.
translate.label.attr.clone:
BV7
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Human umbilical vein EC
Isotype:
IgG1
Physical State:
Liquid
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody stains the extracellular domain of beta-1 integrin. The monoclonal antibody BV7 does not recognize α5β1 complex and not the cytoplasmic part of theβ1-subunit. Monoclonal antibody BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does
Storage Conditions:
2-8[o]C
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody