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Antibodies

CD3 epsilon antibody

Product Sizes
100 ul
£458.00
GTX53910-100UL
About this Product
SKU:
GTX53910
Additional Names:
CD3e molecule , IMD18 , T3E , TCRE
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-207 of human CD3E (NP_000724.1).
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody