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Antibodies

IL10 Receptor alpha antibody [7Q35]

Product Sizes
50 ug
£660.00
GTX52812-50UG
About this Product
SKU:
GTX52812
Additional Names:
CD210 , CD210a , CDW210A , HIL10R , IL10R , IL10R1 , IL10RA , interleukin 10 receptor subunit alpha , IL10 Receptor alpha , CDw210a
Application:
Western Blot
Buffer:
PBS, no preservatives.
translate.label.attr.clone:
7Q35
Clonality:
Monoclonal
Concentration:
500 ug/ml
Extra Details:
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
Host:
Mouse
Immunogen:
Human recombinant IL-10 R A Alpha EC domain
Isotype:
IgG2
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody