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Antibodies

IL1 beta antibody [4M27]

Product Sizes
50 ug
£660.00
GTX52805-50UG
About this Product
SKU:
GTX52805
Additional Names:
IL1 , IL1B , IL1BETA , IL1F2 , interleukin 1 beta , IL1 beta , IL-1B
Application:
Block/Inhibit/Neutralise, IHC-Frozen, Western Blot
Buffer:
PBS, no preservatives.
translate.label.attr.clone:
4M27
Clonality:
Monoclonal
Concentration:
500 ug/ml
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Human recombinant IL-1B Beta
Isotype:
IgG2
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody