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Antibodies

GITR antibody [7R12]

Product Sizes
50 ug
£660.00
GTX52766-50UG
About this Product
SKU:
GTX52766
Additional Names:
AITR , CD357 , GITR , GITRD , TNF receptor superfamily member 18 , TNFRSF18
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Western Blot
Buffer:
PBS, no preservatives.
translate.label.attr.clone:
7R12
Clonality:
Monoclonal
Concentration:
500 ug/ml
Extra Details:
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Host:
Mouse
Immunogen:
Human recombinant TNFRSF18 EC domain
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody