IL10 Receptor alpha (phospho Ser319/323) antibody
Product Sizes
100 ul
£458.00
GTX50361-100UL
About this Product
- SKU:
- GTX50361
- Additional Names:
- interleukin 10 receptor subunit alpha , CD210 , CD210a , CDW210A , HIL-10R , IL-10R1 , IL10R
- Application:
- Western Blot
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 319/Serine 323 (D-S(p)-G-F-G-S(p)-T) derived from human IL10 Receptor alpha.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Download
