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Antibodies

CD3 antibody [CD3-12] (FITC)

Product Sizes
25 ug
£218.00
GTX43629-25UG
About this Product
SKU:
GTX43629
Additional Names:
T3E Antibody , TCRE Antibody , CD3e molecule, epsilon (CD3-TCR complex) Antibody , CD3E Antibody
Application:
Flow Cytometry
Buffer:
PBS, 1% BSA, 0.09% Sodium azide.
translate.label.attr.clone:
CD3-12
Clonality:
Monoclonal
Conjugate:
FITC
Concentration:
0.1 mg/ml
Extra Details:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Host:
Rat
Immunogen:
Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC )
Isotype:
IgG1
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Amphibian, Avian, Bovine, Canine, Feline, Horse, Human, Mouse, Non-human Primate, Other Mammal, Porcine, Rabbit
Shipping Conditions:
Blue Ice
Specificity:
This antibody raised against a peptide representing an invariant cytoplasmic sequence within the CD3ε chain recognizes human CD3ε.
Storage Conditions:
2-8[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light., -20[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light.
Supplier:
GeneTex
Type:
Antibody: Monoclonal Antibody