CD3 epsilon antibody [UCHT1] (Low endotoxin, azide free)
Product Sizes
100 ug
£372.00
GTX42102-100UG
About this Product
- SKU:
- GTX42102
- Additional Names:
- CD3e molecule , IMD18 , T3E , TCRE
- Application:
- Flow Cytometry, IHC-Frozen
- Buffer:
- PBS, no preservatives.
- translate.label.attr.clone:
- UCHT1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Protein A Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds to a region in the ectodomain of human CD3ε and has been shown to bind to a discontinuous epitope near an acidic region of CD3ε opposite the dimer interface.
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
