IL10 antibody [JES3-9D7] (Low endotoxin, azide free)
Product Sizes
500 ug
£907.00
GTX39969-500UG
About this Product
- SKU:
- GTX39969
- Additional Names:
- interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
- Buffer:
- PBS, no preservatives.
- translate.label.attr.clone:
- JES3-9D7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- Host:
- Rat
- Immunogen:
- Recombinant human IL-10.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Clone JES3-9D7 is reported to act as a neutralising antibody (Othieno et al. 1999).
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- GeneTex
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Download
