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Product Sizes
100 ul
£486.00
GTX33963-100UL
About this Product
SKU:
GTX33963
Additional Names:
interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF
Application:
IHC-Paraffin
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Host:
Rabbit
Immunogen:
Recombinant protein of human IL10.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
GeneTex
Type:
Antibody: Polyclonal Antibody