Axin 2 blocking peptide
Product Sizes
50 ug
£196.00
GTX31822-PEP-50UG
About this Product
- SKU:
- GTX31822-PEP
- Additional Names:
- Axin 2 , Axil , Odcrcs , Axin2
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Concentration:
- 200 ug/ml
- Extra Details:
- The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008]
- Immunogen:
- axin 2
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- GeneTex
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:Download
